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Iran and Israel Edge Closer to All-Out War: A Dangerous Escalation in the Middle East

by Li Li
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Smoke rising from buildings in Tel Aviv following Iranian missile strike during June 2025 Israel-Iran conflict

In a dramatic and dangerous turn of events, the Middle East is witnessing an unprecedented direct military conflict between Israel and Iran, bringing both countries to the edge of a full-scale war. With over 220 Iranians and 24 Israelis killed so far, including women, children, and top military officials, the crisis has rapidly escalated from targeted strikes to widespread devastation across multiple cities.

The Latest: Missile Barrages and Retaliation

In the early hours of June 16, Iran launched a new barrage of ballistic missiles targeting Israel’s major urban centers, including Tel Aviv, Haifa, and Petah Tikva. At least eight Israelis were confirmed dead from this latest attack, with dozens wounded, many by flying glass and debris. Some of the victims were elderly, and others were found under rubble in northern Israel.

Among the wounded, at least 87 people were hospitalized, with reports of serious facial injuries in some cases. Iranian missiles even struck near the US Embassy in Tel Aviv, causing minor damage.

In response, the Israeli military launched retaliatory air raids, reportedly destroying over 120 Iranian missile launch sites and claiming to have achieved “full air supremacy” over Tehran. Israeli Defense Minister Israel Katz warned Tehran’s residents to evacuate, saying they will “pay the price” for Iran’s aggression, though he later walked back his comments to stress that civilians were not direct targets.

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Iran: Civilian and Military Targets Hit

Iran’s cities are now reeling under repeated Israeli strikes. The Iranian capital, Tehran, and cities like Kermanshah and Isfahan have been severely impacted. A missile attack on Farabi Hospital in Kermanshah left the facility heavily damaged, with distressing images showing blood-stained floors and shattered glass.

Over 220 people have died in Iran, including 70 women and children and three senior commanders of the Islamic Revolutionary Guard Corps (IRGC). Reports also confirm Israeli strikes on university buildings, oil depots, and residential neighborhoods, triggering widespread anger across Iran.

Iranian President Masoud Pezeshkian addressed the nation, urging unity and pledging continued resistance: “Every fallen martyr will be followed by hundreds… We will hold our ground.”

Nuclear Sites Under Fire, NPT Exit Considered

One of the gravest concerns emerging is the targeting of Iran’s nuclear facilities, including Natanz, Fordow, and Isfahan. The IAEA confirmed damage to above-ground enrichment buildings and electricity infrastructure at Natanz, though radiation levels remain normal.

Meanwhile, Iran’s Parliament is drafting a bill that could see Tehran withdraw from the Nuclear Non-Proliferation Treaty (NPT). While Iranian officials reiterated they are not pursuing nuclear weapons, such a move would mark a sharp escalation in global nuclear tensions.

Global Response: Condemnations and Warnings

  • UN Rights Chief Volker Türk expressed “deep concern” and condemned both nations for violating international law and targeting civilians.
  • The G7 Summit in Canada is prioritizing the crisis, with world leaders calling for de-escalation but reaffirming Israel’s right to self-defense.
  • China’s Foreign Ministry warned the region could descend into greater turmoil and urged immediate talks.
  • The US Embassy in Israel remains closed, with minor damage reported but no injuries.

Regional Spillover: Drone Strikes and Flotilla Fallout

The conflict is already drawing in regional actors:

  • Missiles from Yemen were intercepted by Israeli defense systems.
  • The Madleen aid flotilla, with activists like Greta Thunberg, was intercepted by Israeli forces and its members deported.
  • Poland, India, and China are evacuating citizens, with several land border crossings to Jordan remaining open.

Voices from the Ground: Anger, Exhaustion, and Fear

In Israel:

Air raid sirens now punctuate daily life. Schools and businesses are closed, and rescue teams continue to dig through rubble. Journalist Gideon Levy noted, “The price for civilians this time may be higher than ever. Unlike Gaza or Lebanon, this is Tel Aviv.”

In Iran:

Outrage is growing. Civilian casualties, infrastructure loss, and power outages are widespread. “They hit oil depots, universities, even children,” said a Tehran resident. Iranian media also reported the execution of a Mossad spy and the arrests of suspected collaborators.

Strategic Implications: Miscalculations and No End in Sight

Analysts warn that the crisis could spiral further:

  • Alex Vatanka, from the Middle East Institute, emphasized that Iran lacks strong allies, while Israel has backing from the US and Europe.
  • Trita Parsi of the Quincy Institute said Israel underestimated Iran’s capability to hit back effectively.
  • Israeli military analyst Elijah Magnier warned that “this is only the beginning,” with no exit strategy in sight.
Smoke rising from buildings in Tel Aviv following Iranian missile strike during June 2025 Israel-Iran conflict

Conclusion: Diplomacy or Disaster?

The Iran-Israel confrontation is now one of the most dangerous conflicts of the 21st century. With each side vowing further escalation and the global community largely divided, the risk of a broader Middle East war looms large. The world must act urgently. Words are no longer enough. Whether through the UN, the G7, or regional mediation, diplomacy must be given a last chance before this conflict consumes not just Iran and Israel, but an already volatile region.


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Author Profile

Li Li
Li Li
Li Li, associate professor and master’s supervisor at Southwest University. B.A. in English for Education from Southwest Normal University, M.A. in English Translation and Interpretation from China Foreign Affairs University, Ph. D. in Japanese Cultural History from Nankai University (all above are in China). Also has studied at Osaka Sangyo University and Kokugakuin University in Japan and been a Fulbright visiting scholar to Western Kentucky University in US. A multidisciplinary and versatile instructor with a trilingual mastery of Chinese, English and Japanese, known for Combining foreign language teaching with history and humanity cultivation. Academic researches center on Japanese history, international relations and Western culture studies. Work experiences include teaching at Capital Normal University, Chongqing Normal University, and Southwest University. Has published multiple academic papers, translated works, authored or co-edited several textbooks and monographs; provided language services for several high-level and high-profile international events.

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